154590-35-9, tert-Butyl 4-(4-amino-2-fluorophenyl)piperazine-1-carboxylate is a piperazines compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
STEP B: 2-ethyl-N-(3-fluoro-4-piperazin-1-yl-phenyl)-butyramide.To 4-(2-fluoro-4-methylamino-phenyl)-piperazine-1 -carboxylic acid tert- butyl ester prepared as in STEP A above and TEA (10.0 mmol) in CH2CI2 (50 mL) was added 2-ethyl-butyryl chloride (10.0 mmol). The resulting mixture was stirred at room temperature for 16 h. H2O (10 mL) was then added, the organic layer was separated. After concentration, the semi-solid was collected and re- dissolved into CF3COOH/CH2CI2 (10/50 mL). The resulting mixture was stirred at room temperature for 16 h, then concentrated to yield the title compound.
The synthetic route of 154590-35-9 has been constantly updated, and we look forward to future research findings.
Reference£º
Patent; JANSSEN PHARMACEUTICA N.V.; WO2009/79597; (2009); A1;,
Piperazine – Wikipedia
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