192130-34-0, tert-Butyl 4-(2-aminoethyl)piperazine-1-carboxylate is a piperazines compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
General procedure: One pot method was adopted for synthesis of 2a-k. Firstly, in a50 ml round-bottom flask, appropriate primary amine 1a-k(3.125 mmol), triethylamine (6.25 mmol) and CS2 (6.25 mmol) weredissolved in ethanol (15 mL). The reaction mixture was stirred for3 h at room temperature. Upon completion of the reaction, di-tertbutyldecarbonate (8.5 mmol), dissolved in absolute ethanol, wasadded followed by the immediate addition of a catalytic amount of4-dimethylaminopyridine (0.425 mmol). After the reaction mixturewas kept for further 30 min at room temperature, the solvent wasdistilled off under reduced pressure, and the residue was purifiedby column chromatography (petroleum ether/ethyl acetate= 4:1)to afford the corresponding 2a-k in 48-66% yield.
192130-34-0 tert-Butyl 4-(2-aminoethyl)piperazine-1-carboxylate 1514400, apiperazines compound, is more and more widely used in various.
Reference£º
Article; He, Zhangxu; Qiao, Hui; Yang, Feifei; Zhou, Wenjuan; Gong, Yunpeng; Zhang, Xinhui; Wang, Haojie; Zhao, Bing; Ma, Liying; Liu, Hong-min; Zhao, Wen; European Journal of Medicinal Chemistry; vol. 184; (2019);,
Piperazine – Wikipedia
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