Downstream synthetic route of 67455-41-8

67455-41-8 4-(Piperazin-1-yl)aniline 422925, apiperazines compound, is more and more widely used in various.

67455-41-8,67455-41-8, 4-(Piperazin-1-yl)aniline is a piperazines compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

General procedure: Argon was passed through the suspension of bis-chloride (1) (0.419 g, 1 mmol) in dry pyridine(15 mL) at room temperature over 15 min. Amine (2.5 mmol) was added and the reaction mixture wasbubbled with argon for a further 15 min. The mixture was then stirred at room temperature for 7 days.The solid product was filtered off and washed with dry ether. The raw product was purified throughrecrystallization from ethanol.

67455-41-8 4-(Piperazin-1-yl)aniline 422925, apiperazines compound, is more and more widely used in various.

Reference£º
Article; Zieba, Andrzej; Latocha, Ma?gorzata; Sochanik, Aleksander; Nycz, Anna; Ku?mierz, Dariusz; Molecules; vol. 21; 11; (2016);,
Piperazine – Wikipedia
Piperazines – an overview | ScienceDirect Topics