30459-17-7, 1-(4-Trifluoromethylphenyl)piperazine is a piperazines compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
General procedure: To the chloro compounds (1.00 mmol) in toluene, were added piperazines 8a-j (1.0 mmol) at room temperature. The reaction mixture was heated at 110 oC for overnight. After completion (TLC), the reaction mixture was extracted with ethyl acetate and water. The organic layer was separated and dried over anhydrous Na2SO4, evaporated to dryness. The residue was purified with column chromatography using an eluent of 25% ethyl acetate in hexane to furnish the compounds with moderate to good yields (64-82%)., 30459-17-7
30459-17-7 1-(4-Trifluoromethylphenyl)piperazine 121718, apiperazines compound, is more and more widely used in various.
Reference£º
Article; Banu, Saleha; Bollu, Rajitha; Naseema, Mohammad; Gomedhika, P. Mary; Nagarapu, Lingaiah; Sirisha; Kumar, C. Ganesh; Gundasw, Shravan Kumar; Bioorganic and Medicinal Chemistry Letters; vol. 28; 7; (2018); p. 1166 – 1170;,
Piperazine – Wikipedia
Piperazines – an overview | ScienceDirect Topics