170911-92-9, tert-Butyl 4-(4-aminophenyl)piperazine-1-carboxylate is a piperazines compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
c 1-(4-Acetaminophenyl)-4-tert-butyloxycarbonylpiperazine 2.8 g (0.01 mol) of 1-(4-aminophenyl)-4-tert-butyloxycarbonylpiperazine and 0.78 g=0.7 ml (0.01 mol) of acetyl chloride are dissolved in 50 ml of dry dimethylformamide, 1.3 g=1.8 ml (0.013 mol) of triethylamine are added dropwise with stirring and at room temperature and the mixture is stirred further overnight. It is then concentrated to dryness in vacuo and the residue is partitioned between ethyl acetate and 1N hydrochloric acid. The combined organic extracts are washed with saturated sodium hydrogen carbonate solution, dried and concentrated to dryness in vacuo. Yield: 2.0 g (62.0% of theory), Melting point: 143 C. Rf: 0.49 (silica gel; methylene chloride/methanol=9:1)
170911-92-9, The synthetic route of 170911-92-9 has been constantly updated, and we look forward to future research findings.
Reference£º
Patent; Karl Thomae; US5994356; (1999); A;,
Piperazine – Wikipedia
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