278788-66-2, (R)-tert-Butyl 3-(hydroxymethyl)piperazine-1-carboxylate is a piperazines compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
6-Fluoro-2-methyl-3-(2-oxiranyl) benzonitrile (prepared as described above, 4.80 g, 27.1 mmol ) and (i?)-4-N-BOC-2-hydroxymethyl- piperazine (8.79g. 40.6 mmol) were suspended in EtOH (30mL) and heated in a microwave apparatus at 150 C for 1 h. The reaction mixture was cooled and evaporated to dryness. The residue was purified by chromatography through a 330 g ISCO Redi-sep column eluting with ethyl acetate to 5% MeOH/ ethyl acetate to yield the title compound. LC-MS: M+l= 394;
278788-66-2, The synthetic route of 278788-66-2 has been constantly updated, and we look forward to future research findings.
Reference£º
Patent; MERCK SHARP & DOHME CORP.; PIO, Barbara; PASTERNAK, Alexander; SHAHRIPOUR, Aurash; TANG, Haifeng; WALSH, Shawn; WO2013/90271; (2013); A1;,
Piperazine – Wikipedia
Piperazines – an overview | ScienceDirect Topics