122833-04-9, 2-Methoxy-4-(4-methylpiperazin-1-yl)aniline is a piperazines compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
A solution of the product of EXAMPLE IF (500 mg, 1.40 mmol), 2-methoxy-4-(4- methylpiperazin- 1 -yl)aniline (321 mg, 1.68 mmol) and ^-toluenesulfonic acid (20 mg, cat.) in ?-butanol (10 mL) was heated at 100C for 18 hours. After cooling, the mixture was poured into saturated aqueous sodium bicarbonate (100 mL) and the solution was extracted with ethyl acetate (3 x 50 mL). The combined organic layers were dried over anhydrous sodium sulfate, filtered and concentrated. The residue was purified by flash chromatography on silica gel (200-300 mesh) eluting with 20/1 dichloromethane/methanol to afford the title compound. MS: 272.2 (M/2+ H+)., 122833-04-9
As the paragraph descriping shows that 122833-04-9 is playing an increasingly important role.
Reference£º
Patent; ABBOTT LABORATORIES; ABBOTT LABORATORIES TRADING (SHANGHAI) COMPANY, LTD.; VASUDEVAN, Anil; PENNING, Thomas Dale; CHEN, Huanming; LIANG, Bo; WANG, Shaohui; ZHAO, Zhongqiang; CHAI, Dikun; YANG, Leifu; GAO, Yingxiang; WO2012/97683; (2012); A1;,
Piperazine – Wikipedia
Piperazines – an overview | ScienceDirect Topics