31166-44-6, 1-Cbz-Piperazine is a piperazines compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
IBenzyl piperazine-1-carboxylate (1.05 mL, 5.25 mmol) and potassium carbonate (1.38 g, 10 mmol) were added to a solution of 4-fluoro-2-methyl-1-nitro-benzene (776 mg, S mmol) in DMF (10 mL) and the resulting mixture was stirred at 100 ¡ãC for 18 h. Water was added to the reaction mixture and extraction performed with ethyl acetate. The combinedorganic layers were washed with brine, dried over sodium sulfate and concentrated in vacuo. The crude product was purified by silica column chromatography (heptane/ethyl acetate = 1/0 to 6/4 v/vpercent) to yield the title compound (1.7S g, 98percent)., 31166-44-6
31166-44-6 1-Cbz-Piperazine 643495, apiperazines compound, is more and more widely used in various fields.
Reference£º
Patent; NETHERLANDS TRANSLATIONAL RESEARCH CENTER B.V.; DE ROOS, Jeroen; UITDEHAAG, Joost, Cornelis, Marinus; DE MAN, Adrianus, Petrus, Antonius; BUIJSMAN, Rogier, Christiaan; ZAMAN, Guido, Jenny, Rudolf; (79 pag.)WO2016/166255; (2016); A1;,
Piperazine – Wikipedia
Piperazines – an overview | ScienceDirect Topics