5521-39-1, 2-(4-(4-Aminophenyl)piperazin-1-yl)ethanol is a piperazines compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
5521-39-1, Into a Microwave vial , 7-Bromo-2-methanesulfinyl-pyrrolo[2,l-f][l,2,4]triazine (0.480 g, 0.00184 mol), 2-[4-(4-Amino-phenyl)-piperazin-l-yl]-ethanol (0.8984 g, 0.004060 mol) and l-Methoxy-2-propanol (3.50 mL, 0.0358 mol) were added. The reaction was microwaved on 300 watts , 1800C for 60 minutes . The solvent was removed under vacuum. The desired product was isolated via ISCO column chromatograpy with DCM and methanol as eluant (0 to 7% methanol). The collected fractions afforded2-{4-[4- (7-Bromo-pyrrolo[2,l-fJ[l,2,4]triazin-2-ylamino)-phenyl]-piperazin- 1-yl} -ethanol as a yellow solid (280mg, 36%).
As the paragraph descriping shows that 5521-39-1 is playing an increasingly important role.
Reference£º
Patent; CEPHALON, INC.; BRESLIN, Henry J.; CHATTERJEE, Sankar; DIEBOLD, James L.; DORSEY, Bruce D.; DUNN, Derek; GINGRICH, Diane E.; HOSTETLER, Greg A.; HUDKINS, Robert L.; HUNTER, Rachael; JOSEF, Kurt; LISKO, Joseph; MESAROS, Eugen F.; MILKIEWICZ, Karen L.; OTT, Gregory R.; SUNDAR, Babu G.; THEROFF, Jay P.; THIEU, Tho; TRIPATHY, Rabindranath; UNDERINER, Theodore L.; WEINBERG, Linda; WELLS, Gregory J.; ZIFICSAK, Craig A.; WO2010/71885; (2010); A1;,
Piperazine – Wikipedia
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