21655-48-1, cis-2,6-Dimethylpiperazine is a piperazines compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
To a solution of the compound obtained in step a (120 mg, 0.42 mmol) in DCE (2 mL), DIPEA (166 mg, 1 .28 mmol), c/’s-2,6-dimethylpiperazine (122 mg, 1 .06 mmol) and NaBH(OAc)3 (181 mg, 0.85 mmol) were added and the mixture was stirred at rt for 16 h. NaHCC>3 sat solution was added, extracted with DCM and the organic layer was concentrated under vacuum. Purification by flash chromatography, silica gel, gradient Hex to 100% acetone afforded the title product (126 mg, 78% yield). HPLC (Method B): Ret, 4.10 min; ESI+- MS m/z, 379.1 (M+H).
21655-48-1, The synthetic route of 21655-48-1 has been constantly updated, and we look forward to future research findings.
Reference£º
Patent; ESTEVE PHARMACEUTICALS, S.A.; ALMANSA-ROSALES, Carmen; CUEVAS-CORDOBES, Felix; (77 pag.)WO2019/77106; (2019); A1;,
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