With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.109-07-9,2-Methylpiperazine,as a common compound, the synthetic route is as follows.
2-Methylpiperazine (0. 5G), 2-AMINO-6-CHLORO-7H-PURINE (0.85g) and Hunigs base (LML) in isopropanol (3ML) and NMP (3ml) was heated at 50 C for 18h. The precipitate was filtered off to give the sub-title compound as a white solid (L. LG). MS (APCI+) 234 [M+H] +, 109-07-9
109-07-9 2-Methylpiperazine 66057, apiperazines compound, is more and more widely used in various fields.
Reference£º
Patent; ASTRAZENECA AB; WO2004/74287; (2004); A1;,
Piperazine – Wikipedia
Piperazines – an overview | ScienceDirect Topics