With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.2762-32-5,Piperazine-2-carboxylic acid,as a common compound, the synthetic route is as follows.
2-PIPERAZINECARBOXYLIC acid and 2-CHLORO-1, 3-pyrimidine were stirred with triethylamine and MeOH. After stirring overnight at reflux, the mixture was filtered and concentrated in vacuo to give the desired compound which was used directly in Step B (MH+ = 209).
2762-32-5, 2762-32-5 Piperazine-2-carboxylic acid 2723758, apiperazines compound, is more and more widely used in various fields.
Reference£º
Patent; PHARMACOPEIA, INC.; WO2004/33440; (2004); A1;,
Piperazine – Wikipedia
Piperazines – an overview | ScienceDirect Topics