5308-25-8, 1-Ethylpiperazine is a piperazines compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
5308-25-8, Step 7: 1-ethyl-4-(5-nitropyridin-2-yl)piperazine 2-Chloro-5-nitropyridine (800 mg, 5.05 mmol) was dissolved in dioxane (20 mL) and then 1-ethylpiperazine (1.7 g, 15.15 mmol) and N,N-diisopropylethylamine (927 mL, 5.05 mmol) were added. The reaction mixture solution was stirred at 70 C. for a day. The reaction solution was cooled to room temperature, diluted with ethyl acetate, and then washed with brine. The organic layer was concentrated by drying with magnesium sulfate. The target compound (1.05 g, 87% yield) was used in the following reaction without purification. MS m/z: 237.51 [M+1].
5308-25-8 1-Ethylpiperazine 79196, apiperazines compound, is more and more widely used in various fields.
Reference£º
Patent; Sim, Tae Bo; Hah, Jung Mi; Choi, Hwan Geun; Ham, Young Jin; Lee, Jung Hun; Park, Dong Sik; Kim, Hwan; US2013/12703; (2013); A1;,
Piperazine – Wikipedia
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