120737-78-2, tert-Butyl 2-methylpiperazine-1-carboxylate is a piperazines compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
To a solution of tert-butyl 2-methylpiperazine-1-carboxylate (500 mg, 2.50 mmol) in EtOH (20 mL) was added 37% formaldehyde aqueous solution (405 mg) and AcOH (0.02 mL, 0.35 mmol). The mixture was stirred for 2 hand NaBH3CN (315 mg, 5.01 mmol) was added. The resulting solution was stirred at room temperature overnight and concentrated under vacuum. The residue was purified by flash chromatography on silica gel eluting with 4% MeOH in DCM. This resulted in 430 mg (80%) of tert-butyl 2,4-dimethylpiperazine-1-carboxylate as colorless oil. LCMS (Method 25) [M+H]+=215.0, RT=1.45 min., 120737-78-2
As the paragraph descriping shows that 120737-78-2 is playing an increasingly important role.
Reference£º
Patent; Genentech, Inc.; Zak, Mark Edward; Ray, Nicholas Charles; Goodacre, Simon Charles; Mendonca, Rohan; Kellar, Terry; Cheng, Yun-Xing; Li, Wei; Yuen, Po-Wai; US2015/336962; (2015); A1;,
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