181955-79-3, 1,4-Di-Boc-piperazine-2-carboxylic acid is a piperazines compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
To a dry flask were added 1, 4-di (tert-butoxycarbonyl) piperazine-2-carboxylic acid (14 g, 42.37 mmol) , potassium carbonate (11.7 g, 84.7 mmol) , acetone (200 mL) , iodomethane (5.3 mL, 85 mmol) in turn, the mixture was stirred at rt for 12 hours. The mixture was filtered, the filtrate was concentrated in vacuo and to the residue was added (200 mL) and water (200 mL) , the mixture was separated into layers, the organic layer was washed with saturated aqueous NaCl and dried over anhydrous sodium sulfate, then concentrated in vacuo to get the title compound as a white solid (13.55 g, 93%) . MS (ESI, pos. ion) m/z: 367.2 [M+Na] +.
181955-79-3, As the paragraph descriping shows that 181955-79-3 is playing an increasingly important role.
Reference£º
Patent; SUNSHINE LAKE PHARMA CO., LTD.; LIU, Xinchang; REN, Qingyun; YAN, Guanghua; GOLDMANN, Siegfried; ZHANG, Yingjun; (253 pag.)WO2019/76310; (2019); A1;,
Piperazine – Wikipedia
Piperazines – an overview | ScienceDirect Topics