314741-40-7, (S)-tert-Butyl 3-(hydroxymethyl)piperazine-1-carboxylate is a piperazines compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
(S)-l-Allyl 4-tert-butyl 2- (hydroxymethyl) piperazine-1 , 4- dicarboxylate (22) was prepared from amino alcoholhydrochloride 21’HCl, applying allyl chloroformate in CH2CI2 in the presence of aqueous NaHCO3 solution; as leading references cf. T. W. Greene, P. G. M. Wuts, Protective Groups in Organic Synthesis, 3rd edition, John Wiley & Sons, 1999;P.J. Kocienski, Protecting Groups, 3rd edition, Georg Thieme Verlag, 2005.Data of 22: Ci4H24N2O5 (300.4): LC-MS (method 9a): Rt = 1.70, 201 ([M+H]+). 1H-NMR (DMSO-d6): 5.90 (m, 1 H), 5.29 (qd, J = 1.7,17.3, 1 H), 5.18 (qd, J = 1.5, 10.5, 1 H), 4.81 (t, J = 4.9, 1 H), 4.53 (d-like m, J ca . 5.1, 2 H), 4.04-3.75 (br. m, 4 H), 3.39 (m, 2 H), 2.95-2.70 (br. m, 3 H), 1.40 (s, 9 H).
314741-40-7, The synthetic route of 314741-40-7 has been constantly updated, and we look forward to future research findings.
Reference£º
Patent; POLYPHOR AG; OBRECHT, Daniel; ERMERT, Philipp; OUMOUCH, Said; LACH, Franck; LUTHER, Anatol; MARX, Karsten; MOeHLE, Kerstin; WO2011/15241; (2011); A1;,
Piperazine – Wikipedia
Piperazines – an overview | ScienceDirect Topics