170911-92-9, tert-Butyl 4-(4-aminophenyl)piperazine-1-carboxylate is a piperazines compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
General procedure: To a solution of 2a (1.0 g, 3.6 mmol) in dichloromethane (30 mL)was added 1,1?-thiocarbonyldiimidazole (1.2 g, 7.2 mmol) at roomtemperature. The reaction mixture was stirred at room temperature for1 h. The solvent was removed in vacuo and the residue was purified bysilica gel chromatography (Developing solvent: petroleum ether (PE)/ethyl acetate (EA)=20/1) to give 3a (1.0 g, yield 87.2%). 1H NMR(300 MHz, DMSO-d6): delta 1.42 (s, 9H), 3.08-3.23 (m, 4H), 3.37-3.52 (m,4H), 6.96 (d, J=8.7 Hz, 2H), 7.29 (d, J=8.7 Hz, 2H)., 170911-92-9
The synthetic route of 170911-92-9 has been constantly updated, and we look forward to future research findings.
Reference£º
Article; Bao, Jiyin; Liu, Haichun; Zhi, Yanle; Yang, Wenqianzi; Zhang, Jiawei; Lu, Tao; Wang, Yue; Lu, Shuai; Bioorganic Chemistry; vol. 94; (2020);,
Piperazine – Wikipedia
Piperazines – an overview | ScienceDirect Topics