13484-40-7, 1-(2-Methoxyethyl)piperazine is a piperazines compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
Acetic acid (5.76 g, 96 mmole) was added to a suspension of aldehyde (10 g, 24 mmole) and piperazine (6.91 g, 48 mmole) in NMP (150 mL). The reaction was stirred at room temp for 16h then treated with NaB (OAc) 3H (12.7 g, 60 mmole). The reaction was stirred at room temp for 20h during which time the reaction becomes very viscous. 1N NAOH (200 mL) was then added and the reaction was stirred for LH. The reaction was then poured onto H20 (750 mL) and filtered. The solid was washed with HO (2 x 350 mL), ETOH (100 mL), and ET20 (200 mL). The solid was then dried under vacuum to yield the desired amine as the free base (9.98 g, 76%).
13484-40-7, The synthetic route of 13484-40-7 has been constantly updated, and we look forward to future research findings.
Reference£º
Patent; GPC BIOTECH, INC.; WO2004/92139; (2004); A2;,
Piperazine – Wikipedia
Piperazines – an overview | ScienceDirect Topics