20327-23-5, 1-Cyclopropylpiperazine is a piperazines compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
20327-23-5, A mixture of the chloropyrimidine (200 mg, 0.38 mmol), the piperazine (238 mg, 1.88 mmol) and N,N-diisopropylethylamine (0.26 mL, 1.51 mmol) in DMSO (1.5 mL) was heated in a sealed tube at 110 C for 2 h. The reaction was cooled to room temperature and diluted with water. The layer was then extracted with EtOAc (x2). The combined organic layers were washed with water and brine, dried over MgS04, filtered and concentrated to leave a residue which was used purified by column chromatography (Si02; elution with 2:1 hexane:EtOAc) to yield the desired adduct. LCMS 621 [M+H]+.
As the paragraph descriping shows that 20327-23-5 is playing an increasingly important role.
Reference£º
Patent; MERCK SHARP & DOHME CORP.; MILLER, Michael; BASU, Kallol; DEMONG, Duane; SCOTT, Jack; LI, Wei; HARRIS, Joel; STAMFORD, Andrew; POIRIER, Marc; TEMPEST, Paul; WO2014/137719; (2014); A1;,
Piperazine – Wikipedia
Piperazines – an overview | ScienceDirect Topics