112257-12-2, tert-Butyl 4-(2-bromoacetyl)piperazine-1-carboxylate is a piperazines compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
A suspension of tert-butyl 4-(2-azidoacetyl)pipera-zine-1-carboxylate (2.92 g, 9.51 mmol) and sodium azide(1.54 g, 23.7 mmol) in CH3CN (47 mE) was refluxed for 1hour and cooled to room temperature. The reaction mixturewas diluted with EtOAc, washed with water and brine, driedover Na2504, filtered and concentrated in vacuo. The residuewas purified by recrystallization from EtOAc and hexanes toafford tert-butyl 4-(2-azidoacetyl)piperazine- 1 -carboxylate(2.28 g, 89%) as a white solid. ?H-NMR (CDC13, Varian, 400MHz): oe 1.47 (9H, s), 3.33-3.38 (2H, m), 3.42-3.50 (4H, m),3.58-3.66 (2H, m), 3.95 (2H, s)., 112257-12-2
As the paragraph descriping shows that 112257-12-2 is playing an increasingly important role.
Reference£º
Patent; HANDOK INC.; CMG Pharmaceutical Co., Ltd.; Kim, Moonsoo; Lee, Chaewoon; Lee, Gilnam; Yoon, Cheolhwan; Seo, Jeongbeob; Kim, Jay Hak; Lee, Minwoo; Jeong, Hankyul; Choi, Hyang; Jung, Myung Eun; Lee, Ki Nam; Kim, Hyun Jung; Kim, Hye Kyoung; Lee, Jae Il; Lee, MinWoo; Kim, Misoon; Choi, Soongyu; (124 pag.)US2016/168156; (2016); A1;,
Piperazine – Wikipedia
Piperazines – an overview | ScienceDirect Topics