923565-99-5,923565-99-5, (R)-1-Cbz-2-methylpiperazine is a piperazines compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
Description 27: Phenylmethyl (2R)-2-methyl-4-({4-[2-(methyloxy)-2-oxoethyl]phenyl}methyl)-1- piperazinecarboxylate (D27). A mixture of D16 (243mg, 1mmol), diisopropylethylamine (174ul, 1mmol) 1,1- dimethylethyl (2R)-2-methyl-1-piperazinecarboxylate (234mg, 1mmol) in DMF was stirred at room temperature for 1 h then allowed to stand overnight. The solvent was removed in vacuo, then the residue was diluted with water (20ml) and extracted with EtOAc (2x20ml). The combined organic extracts were dried (MgSO4) and concentrated in vacuo to give the title compound as a yellow oil (383mg). deltaH (CDCI3, 250MHz) 7.21-7.40 (9H, m), 5.13 (2H, AB) 4.29 (1 H1 m), 3.91 (1 H, m), 3.70 (3H, s), 3.62 (2H, s), 3.43 (2H, m), 3.20 (1 H1 m), 2.78 (1H1 m), 2.62 (1 H1 m), 2.05-2.18 (2H1 m), 1.29 (3H1 d).
The synthetic route of 923565-99-5 has been constantly updated, and we look forward to future research findings.
Reference£º
Patent; GLAXO GROUP LIMITED; WO2007/12479; (2007); A2;,
Piperazine – Wikipedia
Piperazines – an overview | ScienceDirect Topics