59702-07-7, 1-Methylpiperazin-2-one is a piperazines compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
59702-07-7, A solution of 5 – ((2,4-dioxo-3,4-dihydroquinazolin-1 (211) -yl) methyl) -2-fluorobenzoic acid, EDC (123 mg, 0.64 mmol ), H0Bt (86 mg, 0.64 mmol) and DIEA (125 mg, 0.96 mmol)In a flask, about 3 mL of anhydrous DMF was added, stirred at room temperature for 15 min, followed by the dropwise addition of 1-methyl-niazin-2-one (225 mg,1.97 mmol) in DMF was added to the reaction solution, stirred overnight at r.t. The reaction was poured into 100 mL of water and treated with 100 mL of DCMThe organic layer was washed successively with water (100 mL), saturated NaCl (100 mL) and water (100 mL), concentrated under reduced pressure and subjected to column chromatography to give the title compound.
59702-07-7 1-Methylpiperazin-2-one 4399042, apiperazines compound, is more and more widely used in various fields.
Reference£º
Patent; Chinese Academy Of Medical Sciences Pharmaceutical Institute; Xu Boling; Chen Xiaoguang; Zhou Jie; Ji Ming; Yao Haiping; Zhou Qin; (57 pag.)CN107098886; (2017); A;,
Piperazine – Wikipedia
Piperazines – an overview | ScienceDirect Topics