With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.934-98-5,2-(4-Methylpiperazin-1-yl)ethanamine,as a common compound, the synthetic route is as follows.
General procedure: I-c (0.6 g, 2.8 mM), 2-methoxyethanol (1.3 g, 17 mM) and sodium hydride (0.1 g, 2.8 mM, 60percent) in ethanol were heated to reflux for 5 h. The mixture was evaporated in vacuo and purified by silica gel column chromatography to get I-d-02 (0.6 g, 78.5percent) as a white solid., 934-98-5
As the paragraph descriping shows that 934-98-5 is playing an increasingly important role.
Reference£º
Article; Wang, Lu; Zhang, Qing; Zhu, Gaoyuan; Zhang, Zhimin; Zhi, Yanle; Zhang, Li; Mao, Tianxiao; Zhou, Xiang; Chen, Yadong; Lu, Tao; Tang, Weifang; European Journal of Medicinal Chemistry; vol. 130; (2017); p. 86 – 106;,
Piperazine – Wikipedia
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