New learning discoveries about (2S,5R)-tert-Butyl 2,5-dimethylpiperazine-1-carboxylate

As the paragraph descriping shows that 548762-66-9 is playing an increasingly important role.

548762-66-9, (2S,5R)-tert-Butyl 2,5-dimethylpiperazine-1-carboxylate is a piperazines compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

548762-66-9, To a stirred solution of 64 mg (0.3 mmol) tert-butyl (25,5R)-2,5-dimethylpiperazine-1- carboxylate in 2 mL DOE were added at RT 160 pL DIPEA (0.9 mmol, 3 eq) and 86 mg 4-methylbenzenesulfonyl chloride (0.45 mmol, 1.5 eq) and the mixture was stirred overnight at RT. The organic phase was washed three times with water, dried andevaporated to yield 110 mg (100%) of the crude title compound which was used in the next step without further purification.[C-MS (Method 1): Rt = 1.39 mm; MS (ESIpos): m/z = 369 [M÷H]

As the paragraph descriping shows that 548762-66-9 is playing an increasingly important role.

Reference：
Patent; BAYER PHARMA AKTIENGESELLSCHAFT; KOPPITZ, Marcus; SIEBENEICHER, Holger; STEUBER, Holger; TER LAAK, Antonius; NUBBEMEYER, Reinhard; ROTTMANN, Antje; IRLBACHER, Horst; BADER, Benjamin; PETERS, Michaele; WAGENFELD, Andrea; (74 pag.)WO2018/114672; (2018); A1;,
Piperazine – Wikipedia
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