934-98-5, 2-(4-Methylpiperazin-1-yl)ethanamine is a piperazines compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated,934-98-5
100 mg of intermediate I-24 was dissolved in resulfured dry DMF,Twelve mg of palladium acetate and 36 mg of DPPP (1,3-bis(diphenylphosphino)propane) were added under nitrogen protection.After stirring for 5 minutes,Withdrawal of nitrogen,Charge CO,After multiple replacements,400 mul of triethylamine and 186 mg of 2-(4-methylpiperazin-1-yl)ethanamine are added,Stir overnight at 80 °C in an oil bath.TLC showed that after the reaction,Take CO,Evaporate the reaction solution under reduced pressureTo the residue was added 30 ml of ethyl acetate and 20 ml of water.Insoluble material was removed by filtration.The filtrate is extracted and separated from the organic layer.dry,Column chromatography after concentration gave 83 mg of compound C-4 (oil, yield 61percent).
934-98-5 2-(4-Methylpiperazin-1-yl)ethanamine 70284, apiperazines compound, is more and more widely used in various fields.
Reference：
Patent; Chinese Academy Of Sciences Shanghai Pharmaceutical Institute; Hu Youhong; Geng Meiyu; Xing Weiqiang; Ding Jian; Ai Jing; (86 pag.)CN103664895; (2018); B;,
Piperazine – Wikipedia
Piperazines – an overview | ScienceDirect Topics