Analyzing the synthesis route of 3-(4-Methylpiperazin-1-yl)propan-1-ol

The synthetic route of 5317-33-9 has been constantly updated, and we look forward to future research findings.

5317-33-9, 3-(4-Methylpiperazin-1-yl)propan-1-ol is a piperazines compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated,5317-33-9

Example 33; 4-(3-Chloro-phenyl)-2-{6-[3-(4-methyl-piperazin-1-yl)-propoxy]-benzoimidazol-1-yl}-thiazole-5-carboxylic acid amide (I.33); Step 1; To a mixture of 0.158 g (1 mmole) of 3-(4-methyl-piperazin-1-yl)-propan-1-ol, and 5 mL of pyridine was added 0.001 g of 4-dimethylaminopyridine and 0.190 g (1 mmole) of p-toluenesulphonyl chloride. The mixture was stirred at ambient temperature overnight and then concentrated under reduced pressure. The residue was taken up in 20 mL of dichloromethane and washed once with 10 mL of saturated sodium bicarbonate, twice with 10 mL of water, and then brine, dried over anhydrous magnesium sulfate, filtered and concentrated under reduced pressure to give 0.248 g of 3-(4-methyl-piperazin-1-yl)-propyl ester as a colorless oil.

The synthetic route of 5317-33-9 has been constantly updated, and we look forward to future research findings.

Reference:
Patent; Cai, Jianping; Chen, Shaoqing; Chen, Yi; Chu, Xin-Jie; Goodnow, JR., Robert Alan; Le, Kang; Luk, Kin-Chun; Mischke, Steven Gregory; Wovkulich, Peter Michael; US2010/160308; (2010); A1;,
Piperazine – Wikipedia
Piperazines – an overview | ScienceDirect Topics