170911-92-9, tert-Butyl 4-(4-aminophenyl)piperazine-1-carboxylate is a piperazines compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
170911-92-9, Step 3. 4-[4-(6-Bromo-imidazo[1,2-a]pyrazin-8-ylamino)-phenyl]-piperazine-1-carboxylic acid tert-butyl ester [0167] A mixture of 6, 8-dibromoimidazo [1, 2-a] pyrazine (12. 5 MMOL), 4- (4-AMINO- PHENYL)-PIPERAZINE-L-CARBOXYLIC acid tert-butyl ester (12) (13. 1 mmol), potassium carbonate (25 mmol), acetonitrile (50 ML) and N, N-DIMETHYLACETAMIDE (20 mL) is heated at 65 C for 16 hrs. The mixture is cooled to room temperature, treated water (100 mL), and extracted with ethyl acetate (3 x 80 mL). The extracts are washed with water (3 x 60 mL) and brine (1 x 60 mL), dried over magnesium sulfate, and concentrated in vacuo. The residue is’ chromatographed over silica gel, eluting with ethyl acetate, to give 4- [4- (6-bromo- imidazo [1, 2-a] pyrazin-8-ylamino)-phenyl]-piperazine-1-carboxylic acid tert-butyl ester (13) as a light brown foam.
As the paragraph descriping shows that 170911-92-9 is playing an increasingly important role.
Reference：
Patent; CELLULAR GENOMICS, INC.; WO2005/14599; (2005); A1;,
Piperazine – Wikipedia
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