30459-17-7, 1-(4-Trifluoromethylphenyl)piperazine is a piperazines compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
General procedure: The mixture of Pd2(dba)3 (377 mg, 0.410 mmol), piperidine (500 mg, 5.87 mmol), t-BuOK (851 mg, 7.58 mmol), X-Phos (418 mg, 0.877 mmol) and intermediate M-2 (1000 mg, 3.35 mmol) in toluene (40 mL) was heated under a nitrogen atmosphere at 110 C until complete by TLC. Upon completion, the reaction solution was cooled to ambient temperature, concentrated under vacuum, and purified by flash chromatography (3:1 petroleum ether: ethyl acetate eluent) to yield N-(2,6-dimethyl-4-(piperidin-1-yl)phenyl)-3,3-dimethylbutanamide (293mg, 29% yield)., 30459-17-7
As the paragraph descriping shows that 30459-17-7 is playing an increasingly important role.
Reference：
Article; Yang, Shaoning; Lu, Dingqiang; Ouyang, Pingkai; Bioorganic and Medicinal Chemistry Letters; vol. 28; 10; (2018); p. 1731 – 1735;,
Piperazine – Wikipedia
Piperazines – an overview | ScienceDirect Topics