With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.59702-07-7,1-Methylpiperazin-2-one,as a common compound, the synthetic route is as follows.
59702-07-7, EXAMPLE 14 3-(2-Fluorophenyl)-5-(1-methyl-2-oxopiperazin-4-yl)-[1,2,3]triazolo[1,5-a]quinazoline Prepared from 1-methylpiperazin-2(1H)-one as described for Example 1, step c (0.033 g, 73percent). deltaH (360 MHz; DMSO) 2.91 (3H, s), 3.61 (2H, dd, J=6 and 6), 3.96 (2H, dd, J=6 and 6), 4.24 (2H, s), 7.35-7.40 (2H, m), 7.44-7.46 (1H, m), 7.78 (1H, dd, J=7 and 7), 8.06-8.12 (2H, m), 8.23 (1H, d, J=7), 8.59 (1H, d, J=7); m/z (ES+) 377 (M+H+).
As the paragraph descriping shows that 59702-07-7 is playing an increasingly important role.
Reference：
Patent; Chambers, Mark Stuart; Collins, Ian James; Goodacre, Simon Charles; Hallett, David James; Jones, Philip; Keown, Linda Elizabeth; Maxey, Robert James; Street, Leslie Joseph; US2003/45532; (2003); A1;,
Piperazine – Wikipedia
Piperazines – an overview | ScienceDirect Topics