262368-30-9, N-(4-Aminophenyl)-N-methyl-2-(4-methylpiperazin-1-yl)acetamide is a piperazines compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
10.5 [G] (30.0 [MMOL)] of [1-ACETYL-3- (1-ETHOXY-1-PHENYLMETHYLENE)-6-METHOXYCARBONYL-2-] indolinone (for preparation see WO 01/27081 mentioned above) and 8.60 g (33.0 [MMOL)] [N- [ (4-METHYL-PIPERAZIN-1-YL)-METHYLCARBONYL]-N-METHYL-P-PHENYLENEDIAMINE] (for preparation see WO 01/27081 mentioned above) are dissolved in 80 mL of dimethylformamide and stirred for 1 hour at [80C.] After cooling 6.50 mL of piperidine are added and the mixture is stirred for another two hours at ambient temperature. Water is added, the precipitate formed is suction filtered and washed with a little water. The residue is suspended in 200 mL of methanol, suction filtered and washed with cold water and diethyl ether. The substance is [DRIED IN VACUO] at 110 [C.] Yield : 12.4 g (77% of theory), [IR SPECTRUM] : 1610,1655, 1711 cm-1 Tm. p. = [253C] [EMPIRICAL FORMULA : C31H33N504] [ESI] mass spectrum: m/z = 540 [M+H]+ Elemental analysis: calculated: C 68.99 [H-6.] 16 [N 12.] 98 found: C 68.32 H 6.29 N 12.85, 262368-30-9
The synthetic route of 262368-30-9 has been constantly updated, and we look forward to future research findings.
Reference：
Patent; BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG; WO2004/13099; (2004); A1;,
Piperazine – Wikipedia
Piperazines – an overview | ScienceDirect Topics