21043-40-3, 1-Cyclopentylpiperazine is a piperazines compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
To a solution of [2-(4-methyl-naphthalen-1-yl)-3H-imidazol-4-yl]-methanol (50 mg, 0.21 mmol) in 1 ,2-dichloroethane (5 ml) at 0C is added thionylchloride (5 eq.). The resulting mixture is stirred at 50C for 1 hr. Solvent and remaining thionylchloride are evaporated, and the residue is dissolved in acetonitrile (3 ml), followed by the addition of substituted 4-cyclopentylpiperazine (1.0 eq.) and potassium carbonate (2.0 eq.). The resulting mixture is stirred at rt overnight. The reaction is diluted with EtOAc (10 ml), washed with brine, dried, and solvent is removed. The crude product is purified through PTLC to give l-cyclopentyl-4-[2-(4-methyl-naphthalen-1-yl)-3H-imidazol-4- ylmethyl]-piperazine. LCMS 375 (M+ +1).
21043-40-3, As the paragraph descriping shows that 21043-40-3 is playing an increasingly important role.
Reference：
Patent; NEUROGEN CORPORATION; WO2006/89076; (2006); A2;,
Piperazine – Wikipedia
Piperazines – an overview | ScienceDirect Topics