With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.13754-38-6,1-Benzoylpiperazine,as a common compound, the synthetic route is as follows.
3.09 (10.0 mmol) of N-(2-bromoethyl)-2-nitrobenzenesulfonamide,1.90 g (10.0 mmol) of benzoylpiperazine and 2.76 g (20.0 mmol) of potassium carbonate were added toThe reaction was carried out in 150 ml of tetrahydrofuran at room temperature for 2 h, warmed to reflux, and the reaction was followed by TLC.After the completion of the reaction, the solvent was evaporated, evaporated, evaporated, evaporated.Column chromatography, 2.59 g of white solid, yield 62%, 13754-38-6
As the paragraph descriping shows that 13754-38-6 is playing an increasingly important role.
Reference：
Patent; East China University of Science and Technology; Xu Xiaoyong; Li Zhong; Chen Xiulei; Li Wei; Jia Haowu; Cao Xiaofeng; Shao Xusheng; Xu Zhiping; (70 pag.)CN108276352; (2018); A;,
Piperazine – Wikipedia
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