5294-61-1, N-(2,6-Dimethylphenyl)-2-(piperazin-1-yl)acetamide is a piperazines compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
5294-61-1, To a solution of crude N- (4-METHOXYPHENYL)-2-OXIRAN-2-YLACETAMIDE (10) in ethanol (2. 5ML) was added triethylamine (0. 5ML), followed by N- (2, 6-dimethylphenyl) -2- piperazinylacetamide, a compound of fonnula (4) (150mg), and the mixture was heated to reflux for 18 hours. Solvent was removed from the reaction mixture under reduced pressure, and the residue purified by column chromatography on silica gel, eluting with 5% MeOH/dichloromethane, to give 4- (4-1 [N- (2, 6-dimethylphenyl) carbamoyl] methyl}- PIPERAZINYL)-3-HYDROXY-N- (4-METHOXYPHENYL) butanamide, a compound of Formula I as an off- white solid.
The synthetic route of 5294-61-1 has been constantly updated, and we look forward to future research findings.
Reference：
Patent; CV THERAPEUTICS, INC.; WO2004/63180; (2004); A1;,
Piperazine – Wikipedia
Piperazines – an overview | ScienceDirect Topics