21655-48-1, cis-2,6-Dimethylpiperazine is a piperazines compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
0.44 ml of ethyl 4-fluorobenzoate was dissolved in 8 ml of dimethylsulfoxide, 1.370 g of (2S, 6R) -dimethylpiperazine was added,The temperature was raised to 120 C under argon protection, and the mixture was heated for 28 hours. After heating, the reaction solution was diluted with 40 ml of water,Ethyl ester extraction, organic phase after the merger with saturated aqueous sodium chloride solution washed five times, anhydrous sodium sulfate drying, filtration concentrated, residualThe residue was chromatographed (dichloromethane: methanol = 99: 1-97: 3, V / V) to give 0.730 g of a brown oil in a yield of 92.8%., 21655-48-1
21655-48-1 cis-2,6-Dimethylpiperazine 6950261, apiperazines compound, is more and more widely used in various fields.
Reference：
Patent; Chinese Academy Of Sciences Shanghai Pharmaceutical Institute; Duan Wenhu; Geng Meiyu; Zhao Bin; Ding Jian; Ai Jing; Fan Jun; Peng Xia; Yan Wei; Chen Yi; (77 pag.)CN106146493; (2016); A;,
Piperazine – Wikipedia
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