170911-92-9, tert-Butyl 4-(4-aminophenyl)piperazine-1-carboxylate is a piperazines compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
mCPBA (<77% pure) (4.5 mg, assumed 0.020 mmol) in DCM (0.5 ml) was added to a stirred solution of 6- (2 , 6 -dichlorophenyl ) -8-methyl-2- (methylthio)pyrido [4 , 3 -d] pyrimidin-5 (6H) -one (6.1 mg, 0.017 mmol) in toluene (1.0 mL) at RT under nitrogen. After 1.5 h, DIPEA (9.0 mu-,, 0.052 mmol) and tert-butyl 4-(4- aminophenyl) piperazine-l-carboxylate (5.3 mg, 0.019 mmol) [commercially available] in toluene (0.5 ml) were added, successively, and the temperature was increased to 60 C. After 16 h, the reaction mixture was allowed to cool to RT, and was loaded directly onto a column and purified by flash chromatography (0-100%, EtOAc in cyclohexane) to give the title compound (5.4 mg, 54%) as a yellow oil. LCMS (Method A): RT = 1.61 min, m/z = 581, 583 [M+H]+ 170911-92-9, The synthetic route of 170911-92-9 has been constantly updated, and we look forward to future research findings.
Reference：
Patent; ALMAC DISCOVERY LIMITED; O’DOWD, Colin Roderick; ROUNTREE, James Samuel Shane; BURKAMP, Frank; WILKINSON, Andrew John; WO2014/167347; (2014); A1;,
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