154590-34-8, tert-Butyl 4-(2-fluoro-4-nitrophenyl)piperazine-1-carboxylate is a piperazines compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
At room temperature, 3.5 g (10 mmol) of intermediate Ib was dissolved in 35 mL of 90% EtOH and heated to 70 C. 0.44 g (1.5 mmol) of FeCl · 6H2O and 0.038 g (3 mmol) of activated charcoal were added and stirred for 10 min. A solution of 6.73 g (100 mmol) of 80% hydrazine hydrate was added dropwise and heated to 90 C for 2 h. Reaction is completed, the hot filter, the solvent evaporated to dry the crude product, and then add 50mL of crude water, the platform stirring 0.5h, filter, filter cake with a small amount of water rinse, dry pale yellow solid 2.5g, yield 78.6 %, 154590-34-8
The synthetic route of 154590-34-8 has been constantly updated, and we look forward to future research findings.
Reference：
Patent; Shenyang Red Flag Pharmaceutical Co., Ltd.; Li Juan; Yang Bo; Li Xingyuan; Zhang Tiejie; Sun Jukui; (19 pag.)CN107033095; (2017); A;,
Piperazine – Wikipedia
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