120737-59-9, tert-Butyl 3-methylpiperazine-1-carboxylate is a piperazines compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
To a solution OF RAC-3-METHYL-PIPERAZINE-L-CARBOXYLIC acid tert-butyl ester (350 mg, 1.75 mmol) in dimethylformamide (3 ml) were added 2-Iodo-5-methanesulfonyl-benzoic acid (540 mg, 1.67 mmol), N-ETHYLDIISOPROPYLAMINE (1. 8 ml, 10.5 mmol), and TBTU (630 mg, 1.92 mmol). The reaction mixture was then allowed to stir at room temperature for 16 hours. The reaction mixture was then concentrated in vacuo and the residue was purified by column chromatography (SI02, 20g, Heptane/EtOAc 0-100percent) to give the title compound (400 mg, 45 percent). MS (m/e): 526.2 (M+NH4+).
120737-59-9, As the paragraph descriping shows that 120737-59-9 is playing an increasingly important role.
Reference:
Patent; F. HOFFMANN-LA ROCHE AG; WO2005/23260; (2005); A1;,
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