21043-40-3, 1-Cyclopentylpiperazine is a piperazines compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
bf P a6e l henyl)-piperidin-4-yl]-acetic acid (0.11 mmol) in anhydrousDCM (2 mL) is added 1-cyclopentylpiperazine (l.leq.), TEA (0.22 mmol), and BOP (0.14 mmol). The resulting mixture is stirred at rt overnight. DCM is evaporated. The residue is dissolved in EtOAc (20 mL), washed with water (5 mL x 3) and brine, dried over sodium sulfate, and concentrated. The crude product is purified through PTLC to give the title compound. 1H NMR (300 MHz5 CDCl3) delta 7.85 (2H, d), 6.85 (2H, d), 3.89 (2H, br), 3.66 (2H, t), 3.49 (2H, t), 2.91 (2H, dt), 2.46-2.57 (8H, overlapped), 2.26 (2H, d), 2.12 (IH, m), 1.22-1.95 (12H, m); LC-MS (M+l) 398.
21043-40-3, 21043-40-3 1-Cyclopentylpiperazine 806421, apiperazines compound, is more and more widely used in various fields.
Reference：
Patent; NEUROGEN CORPORATION; WO2007/16496; (2007); A2;,
Piperazine – Wikipedia
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