With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.182618-86-6,1-Boc-4-(4-Nitrophenyl)piperazine,as a common compound, the synthetic route is as follows.
The above product 17B was dissolved in methanol (15 mL) and 10% palladium on carbon (150 mg) was added and reacted overnight under hydrogen. The reaction was monitored by TLC and filtered through celite. The filtrate was concentrated to give product 17C.
182618-86-6, 182618-86-6 1-Boc-4-(4-Nitrophenyl)piperazine 3380696, apiperazines compound, is more and more widely used in various fields.
Reference:
Patent; Chengdu Beisikairui Biological Technology Co., Ltd.; Li Dequn; (44 pag.)CN107540636; (2018); A;,
Piperazine – Wikipedia
Piperazines – an overview | ScienceDirect Topics