So far, in addition to halogen atoms, other non-metallic atoms can become part of the aromatic heterocycle, and the target ring system is still aromatic.Herzberg, Gene R.; Rogerson, Minda researched the compound: (S)-Methyl 3-hydroxybutanoate( cas:53562-86-0 ).Application In Synthesis of (S)-Methyl 3-hydroxybutanoate.They published the article 《Use of alcohol oxidase to measure the methanol produced during the hydrolysis of D- and L-methyl-3-hydroxybutyric acid》 about this compound( cas:53562-86-0 ) in Analytical Biochemistry. Keywords: methanol enzymic determination alc oxidase; alc primary enzymic determination oxidase; methyl hydroxybutyrate hydrolysis alc oxidase. We’ll tell you more about this compound (cas:53562-86-0).
An enzymic assay for the measurement of MeOH was developed. The assay uses alc. oxidase and peroxidase coupled to the oxidation of 2,2′-azino-di-(3-ethyl)-benzthiazoline-6-sulfonic acid as the chromogen. The assay is linear up to 50 nmol MeOH in a 200-μL sample and sensitive; 1.25 nmol of MeOH in a 200-μL sample can be measured. The assay is rapid and measurements can be made at any convenient time between 15 min and 4 h after initiation of the reaction. The assay shows highest activity with MeOH but significant activity with other primary alcs. up to 1-butanol. Little activity is shown with secondary alcs. and diols. This assay was used to follow the hydrolysis of the 2 isomers of the Me ester of 3-hydroxybutyric acid.
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Reference:
Piperazine – Wikipedia,
Piperazines – an overview | ScienceDirect Topics