COA of Formula: C8H8FN. So far, in addition to halogen atoms, other non-metallic atoms can become part of the aromatic heterocycle, and the target ring system is still aromatic. Compound: 5-Fluoroindoline, is researched, Molecular C8H8FN, CAS is 2343-22-8, about Re-Catalyzed Annulations of Weakly Coordinating N-Carbamoyl Indoles/Indolines with Alkynes via C-H/C-N Bond Cleavage.
A rhenium-catalyzed [3+2] annulations of N-carbamoyl indoles with alkynes via C-H/C-N bond cleavage, provided rapid access to fused-ring pyrroloindolone derivs I [R1 = H, 6-F, 7-Br, etc.; R2 = R3 = Ph, 4-MeC6H4, 1-naphthyl, etc.]. For the first time, the weakly coordinating O-directing group was successfully employed in rhenium-catalyzed C-H activation reactions, enabled by the unique catalytic ratio of Re2(CO)10, Me2Zn and ZnCl2. Mechanistic studies revealed that aminozinc species played an important role in the reaction. Based on the mechanistic understanding, a more powerful catalytic ratio of Re2(CO)10, [MeZnNPh2]2 and Zn(OTf)2 was devised and applied successfully in the [4+2] annulations of indolines and alkynes affording pyrroloquinolinone derivs II.
As far as I know, this compound(2343-22-8)COA of Formula: C8H8FN can be applied in many ways, which is helpful for the development of experiments. Therefore many people are doing relevant researches.
Reference:
Piperazine – Wikipedia,
Piperazines – an overview | ScienceDirect Topics