Epoxy compounds usually have stronger nucleophilic ability, because the alkyl group on the oxygen atom makes the bond angle smaller, which makes the lone pair of electrons react more dissimilarly with the electron-deficient system. Compound: (S)-1-(Dimethylamino)propan-2-ol, is researched, Molecular C5H13NO, CAS is 53636-17-2, about Gas chromatographic separation of some enantiomers on optically active copper(II) complexes.Synthetic Route of C5H13NO.
Gas chromatog. separation of optically active amino alcs., amines, amino esters, and alcs. was achieved using optically active Cu(II) complexes. The binuclear Cu(II) complex of either (R)-2-(salicylidenamino)-1,1-bis(5-tert-butyl-2-octyloxyphenyl)propan-1-ol or (S)-2-(salicylidenamino)-1,1-diphenylpropan-1-ol was incorporated into the stationary phase on both capillary and packed columns. Separation results for 13 compounds, using the carrier gas, are tabulated. Trimethylsilylation decreased the separation of amino alc. enantiomers, and acylation destroyed it entirely.
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Reference:
Piperazine – Wikipedia,
Piperazines – an overview | ScienceDirect Topics