The reaction of an aromatic heterocycle with a proton is called a protonation. One of articles about this theory is 《Synthesis of 4-Acylchromene via Highly Chemoselective Iodine-Catalyzed Cyclization of Alkynylarylether Dimethylacetals》. Authors are Rodphon, Warabhorn; Thongsornkleeb, Charnsak; Tummatorn, Jumreang; Ruchirawat, Somsak.The article about the compound:2-Bromopriopionaldehydediethylacetalcas:3400-55-3,SMILESS:CC(Br)C(OCC)OCC).Electric Literature of C7H15BrO2. Through the article, more information about this compound (cas:3400-55-3) is conveyed.
A metal-free method for the synthesis of 4-acylchromene derivatives I [R1 = Ph, 4-MeC6H4, 4-FC6H4, etc.; R2 = H, 6-Cl, 7-OMe, etc.] and II [R3 = H, Me, CH2Cl; R4 = H, Me] via highly chemoselective iodine-catalyzed cyclization of alkynylarylether dimethylacetals was reported. A combination of acetone and catalytic I2 lead to selective activation of acetal in alkynylarylether dimethylacetal substrates while alkyne moiety remained intact. Also this method was a safe, cost-effective, convenient and environmentally-friendly.
Here is just a brief introduction to this compound(3400-55-3)Electric Literature of C7H15BrO2, more information about the compound(2-Bromopriopionaldehydediethylacetal) is in the article, you can click the link below.
Reference:
Piperazine – Wikipedia,
Piperazines – an overview | ScienceDirect Topics