Related Products of 53562-86-0. So far, in addition to halogen atoms, other non-metallic atoms can become part of the aromatic heterocycle, and the target ring system is still aromatic. Compound: (S)-Methyl 3-hydroxybutanoate, is researched, Molecular C5H10O3, CAS is 53562-86-0, about A strategy for the stereoselective synthesis of unsymmetric atropisomeric ligands: preparation of NAPhePHOS, a new biaryl diphosphine.
MeO-NAPhePHOS (shown as I) represents the 1st example of atropisomeric diphosphines bearing heterotopic biaryl moieties. The key step of its synthesis is the diastereoselective, intramol., CuI-promoted coupling of 1-iodo-2-naphthol and 2-iodo-3-methoxyphenol connected by a chiral tether. (R,R)-2,4-Pentanediol was used as the chiral auxiliary in this highly selective reaction that leads to a single enantiomer of the title diphosphine. In the Ru-promoted hydrogenations of carbonyl derivatives, NAPhePHOS affords enantioselectivity levels fully comparable to those of the C2-sym. analogs, BINAP and MeO-BIPHEP, resp., thus showing that the lack of C2 symmetry is not detrimental to the catalytic properties of atropisomeric ligands in these hydrogenation reactions.
In addition to the literature in the link below, there is a lot of literature about this compound((S)-Methyl 3-hydroxybutanoate)Related Products of 53562-86-0, illustrating the importance and wide applicability of this compound(53562-86-0).
Reference:
Piperazine – Wikipedia,
Piperazines – an overview | ScienceDirect Topics