So far, in addition to halogen atoms, other non-metallic atoms can become part of the aromatic heterocycle, and the target ring system is still aromatic.Yang, Ren-Yin; Wang, Hui; Xu, Bo researched the compound: 1-(Bromomethyl)-4-iodobenzene( cas:16004-15-2 ).Quality Control of 1-(Bromomethyl)-4-iodobenzene.They published the article 《Base promoted gem-difluoroolefination of alkyl triflones》 about this compound( cas:16004-15-2 ) in Chemical Communications (Cambridge, United Kingdom). Keywords: difluoroalkene preparation; alkyl triflone bromodifluoromethyl trimethylsilane difluoroolefination lithium iodide catalyst. We’ll tell you more about this compound (cas:16004-15-2).
A new synthesis of gem-difluoroalkenes ArC(R)=CF2 [Ar = 4-bromophenyl, naphthalen-2-yl, 5-(methoxycarbonyl)thiophen-2-yl, etc.; R = prop-2-en-1-yl, 3-phenylprop-2-yn-1-yl, (4-methylphenyl)methyl, etc.] from readily available alkyl triflones ArCH(R)S(O)2CF3 and difluorocarbene precursors such as TMSCF2Br has been reported. The reaction, regardless of electronic effect, gives gem-difluoroalkenes ArC(R)=CF2 in good to excellent yields. The mechanism may involve deprotonation of triflones, nucleophilic addition, and the elimination of SO2CF3.
In some applications, this compound(16004-15-2)Quality Control of 1-(Bromomethyl)-4-iodobenzene is unique.If you want to know more details about this compound, you can contact with the author or consult more relevant literature.
Reference:
Piperazine – Wikipedia,
Piperazines – an overview | ScienceDirect Topics