So far, in addition to halogen atoms, other non-metallic atoms can become part of the aromatic heterocycle, and the target ring system is still aromatic.Seebach, Dieter; Zueger, Max researched the compound: (S)-Methyl 3-hydroxybutanoate( cas:53562-86-0 ).Quality Control of (S)-Methyl 3-hydroxybutanoate.They published the article 《Depolymerization of poly[(R)-3-hydroxy-butanoate](PHB)》 about this compound( cas:53562-86-0 ) in Helvetica Chimica Acta. Keywords: depolymerization poly hydroxybutanoate; alkyl hydroxybutanoate enantiomeric. We’ll tell you more about this compound (cas:53562-86-0).
Enantiomerically pure Me, Et, Bu, or 2-methoxyethyl (R)-3-hydroxybutanoates were prepared in 75-90% yields by depolymerization of the title compound, or materials containing it, at 80-160° in MeOH, EtOH, BuOH, or MeOCH2CH2OH with or without cosolvent (ClCH2)2 in the presence of either H2SO4 or (EtO)4Ti catalyst. (S)-3-Hydroxybutanoates were also obtained by yeast reduction of acetoacetates; thus 3-hydroxybutyric acid derivatives are among those useful synthons available in both enantiomeric forms.
Although many compounds look similar to this compound(53562-86-0)Quality Control of (S)-Methyl 3-hydroxybutanoate, numerous studies have shown that this compound(SMILES:C[C@H](O)CC(OC)=O), has unique advantages. If you want to know more about similar compounds, you can read my other articles.
Reference:
Piperazine – Wikipedia,
Piperazines – an overview | ScienceDirect Topics