In organic chemistry, atoms other than carbon and hydrogen are generally referred to as heteroatoms. The most common heteroatoms are nitrogen, oxygen and sulfur. Now I present to you an article called Synthesis and pharmacological evaluation of antioxidant chalcone derivatives of 2(3H)-benzoxazolones, published in 2009, which mentions a compound: 54903-09-2, mainly applied to chalcone derivative benzoxazolone preparation antioxidant activity, Synthetic Route of C9H7NO3.
Chalcones featuring an analgesic/anti-inflammatory pharmacophore, i.e., the 2(3H)-benzoxazolone heterocycle, on the one hand, and a radical scavenger moiety, i.e., 2,6-di-t-butylphenol, on the other hand were synthesized by condensation of a ketone 2(3H)-benzoxazolone precursor with 3,5-di-t-butyl-4-hydroxybenzaldehyde. Among the various methods explored (acid homogeneous or heterogeneous catalysis, base catalysis), heterogeneous catalysis conditions using KSF Montmorillonite were found to be the most convenient. The E-geometry of the so-obtained chalcones was ascertained both by 1H and 13C-NMR spectroscopy as well as B3LYP/6-31G** quantum mechanics calculations Eight chalcones, e.g. I, were pharmacol. evaluated in vitro for their ability to prevent human low-d. lipoprotein (LDL) copper-induced oxidation using Cu2+ as oxidizing agent. I emerged as the most promising agent as it was able to inhibit copper-mediated human LDL oxidation with an activity ten times greater than that of Probucol, a reference antioxidant drug.
After consulting a lot of data, we found that this compound(54903-09-2)Synthetic Route of C9H7NO3 can be used in many types of reactions. And in most cases, this compound has more advantages.
Reference:
Piperazine – Wikipedia,
Piperazines – an overview | ScienceDirect Topics