In organic chemistry, atoms other than carbon and hydrogen are generally referred to as heteroatoms. The most common heteroatoms are nitrogen, oxygen and sulfur. Now I present to you an article called Asymmetric reactions catalyzed by chiral metal complexes. XLIX. Synthesis of atropisomeric biphenylbisphosphine. 6,2′-Bis(diphenylphosphino)-3-methoxy-2,4-dimethyl-4′,6′-bis(trifluoromethyl)-1,1′-biphenyl (FUPMOP) and its use in ruthenium(II)-catalyzed asymmetric hydrogenation of a 3-oxo ester, published in 1991-11-30, which mentions a compound: 53562-86-0, mainly applied to asym hydrogenation oxobutanoate catalyst biphenylbisphosphineruthenium; atropisomeric biphenylbisphosphine ligand synthesis, Quality Control of (S)-Methyl 3-hydroxybutanoate.
New atropisomeric biphenylbisphosphines, 6,2′-bis(diphenylphosphino)-3-methoxy-2,4-dimethyl-4′,6′-bis(trifluoromethyl)-1,1′-biphenyl (FUPMOP) and 2,2′-bis(diphenylphosphino)-4,4′,6,6′-tetrakis(trifluoromethyl)-1,1′-biphenyl (BIFUP), were prepared from 2,3,5-Br(CF3)2C6H2NO2. The FUPMOP-Ru(II) complex was an excellent catalyst for the asym. hydrogenation of MeCOCH2CO2Me.
The article 《Asymmetric reactions catalyzed by chiral metal complexes. XLIX. Synthesis of atropisomeric biphenylbisphosphine. 6,2′-Bis(diphenylphosphino)-3-methoxy-2,4-dimethyl-4′,6′-bis(trifluoromethyl)-1,1′-biphenyl (FUPMOP) and its use in ruthenium(II)-catalyzed asymmetric hydrogenation of a 3-oxo ester》 also mentions many details about this compound(53562-86-0)Quality Control of (S)-Methyl 3-hydroxybutanoate, you can pay attention to it, because details determine success or failure
Reference:
Piperazine – Wikipedia,
Piperazines – an overview | ScienceDirect Topics