Piperazine is an organic compound that consists of a six-membered ring containing two nitrogen atoms at opposite positions in the ring. 103-76-4, formula is C6H14N2O, Name is N-(2-Hydroxyethyl)piperazine. Piperazine exists as small alkaline deliquescent crystals with a saline taste. Synthetic Route of 103-76-4.
Zhu, Li;Zhao, Rui-Han;Li, Yu;Liu, Gong-Qing;Zhao, Yu research published 《 CtD strategy to construct stereochemically complex and structurally diverse compounds from griseofulvin》, the research content is summarized as follows. The Complexity to Diversity (CtD) strategy, for the synthesis of stereochem. complexes I (R = H, C(O)Me, Ph, Bn, etc; R1 = H, Me, n-Bu, Bn, etc.), II, III (R2 = OEt, benzyloxidanyl, morpholin-4-yl, etc.) and cis/trans-IV (R3 = H; R4 = Me, i-Pr; R3R4 = -(CH2)5-) and structurally diverse small mols. from natural products using ring-distortion reactions, was applied in the synthesis of a 47-member compounds I, II, III and cis/trans-IV collection from the natural product griseofulvin. A Tsuji-Trost allylation and oxa-Michael cyclization tandem reaction was used for the first time in the CtD strategy to generate complex ring fused cis/trans-IV .
Synthetic Route of 103-76-4, 1-(2-Hydroxyethyl)piperazine is a useful research compound. Its molecular formula is C6H14N2O and its molecular weight is 130.19 g/mol. The purity is usually 95%.
1-(2-Hydroxyethyl)piperazine is a chemical solvent that is used for the absorption of amines and other compounds. It has been shown to have a high affinity for acidic substances, which may be due to its ability to form hydrogen bonds with them. 1-(2-Hydroxyethyl)piperazine is also used in sample preparation for the analysis of amines and other compounds in fruit extracts. The solubility of 1-(2-Hydroxyethyl)piperazine depends on the experimental conditions, including pH, temperature, and pressure. FT-IR spectroscopy has been used to measure the vibrational modes of 1-(2-Hydroxyethyl)piperazine molecules. The IR spectrum revealed that this compound contains a hydroxyl group and two fatty acid chains with one or more hydroxyl groups at their terminal end. The nmr spectrum showed that 1-(2-Hydroxyethyl)piperazine contains an NH proton as well as, 103-76-4.
Referemce:
Piperazine – Wikipedia,
Piperazines – an overview | ScienceDirect Topics