Xiang, Ming; Pfaffinger, Dana E.; Ortiz, Eliezer; Brito, Gilmar A.; Krische, Michael J. published the artcile< Enantioselective Ruthenium-BINAP-Catalyzed Carbonyl Reductive Coupling of Alkoxyallenes: Convergent Construction of syn-sec,tert-Diols via (Z)-σ-Allylmetal Intermediates>, Application In Synthesis of 374930-88-8, the main research area is benzhydryloxyallene aldehyde ruthenium catalyst diastereoselective enantioselective reductive coupling reaction; aryl alc benzhydryloxyallene ruthenium catalyst diastereoselective enantioselective reductive coupling; benzhydryloxy alkenol preparation.
The first catalytic enantioselective ruthenium-catalyzed carbonyl reductive couplings of allene pronucleophiles was described. Using an iodide-modified ruthenium-BINAP-catalyst and O-benzhydryl alkoxyallene, carbonyl (α-alkoxy)allylation occurs from the alc. or aldehyde oxidation level to form enantiomerically enriched syn-sec,tert-diols. Internal chelation directs intervention of (Z)-σ-alkoxyallylruthenium isomers, which engage in stereospecific carbonyl addition
Journal of the American Chemical Society published new progress about Alkenyl alcohols Role: PRP (Properties), RCT (Reactant), SPN (Synthetic Preparation), RACT (Reactant or Reagent), PREP (Preparation). 374930-88-8 belongs to class piperazines, and the molecular formula is C13H19BrN4O2, Application In Synthesis of 374930-88-8.
Referemce:
Piperazine – Wikipedia,
Piperazines – an overview | ScienceDirect Topics